Publications
Activated Translation Signaling in Placenta from Pregnant Women with Gestational Diabetes Mellitus: Possible Role of Leptin.
Pérez-Pérez A, Maymó JL, Gambino YP, Guadix P, Dueñas JL, Varone CL, Sánchez-Margalet V. Horm Metab Res. 2013 Jun;45(6):436-42.
The Alternative Epac/cAMP Pathway and the MAPK Pathway Mediate hCG Induction of Leptin in Placental Cells.
Maymó JL, Pérez Pérez A, Maskin B, Dueñas JL, Calvo JC, Sánchez Margalet V, Varone CL.
PLoS One. 2012;7(10):e46216. PubMed.
Elsevier Trophoblast Research Award lecture: Molecular mechanisms underlying estrogen functions in trophoblastic cells--focus on leptin expression.
Gambino YP, Maymó JL, Pérez Pérez A, Calvo JC, Sánchez-Margalet V, Varone CL.
Placenta. 2012 Feb;33 Suppl:S63-70. PubMed.
Regulation of leptin expression by 17beta-estradiol in human placental cells involves membrane associated estrogen receptor alpha.
Gambino YP, Pérez Pérez A, Dueñas JL, Calvo JC, Sánchez-Margalet V, Varone CL.
Biochim Biophys Acta. 2012 Apr;1823(4):900-10. Pubmed
Review: Leptin gene expression in the placenta--regulation of a key hormone in trophoblast proliferation and survival.
Maymó JL, Pérez AP, Gambino Y, Calvo JC, Sánchez-Margalet V, Varone CL.
Placenta. 2011 Mar;32 Suppl 2:S146-53. PubMed.
Leptin receptor activation increases Sam68 tyrosine phosphorylation and expression in human trophoblastic cells.
Sánchez-Jiménez F, Pérez-Pérez A, González-Yanes C, Najib S, Varone CL, Sánchez-Margalet V.
Mol Cell Endocrinol. 2011 Jan 30;332(1-2):221-7. PubMed.
Regulation of placental leptin expression by cyclic adenosine 5'-monophosphate involves cross talk between protein kinase A and mitogen-activated protein kinase signaling pathways.
Maymó JL, Pérez Pérez A, Dueñas JL, Calvo JC, Sánchez-Margalet V, Varone CL.
Endocrinology. 2010 Aug;151(8):3738-51. PubMed.
MAPK and PI3K activities are required for leptin stimulation of protein synthesis in human trophoblastic cells.
Pérez-Pérez A, Gambino Y, Maymó J, Goberna R, Fabiani F, Varone C, Sánchez-Margalet V.
Biochem Biophys Res Commun. 2010 Jun 11;396(4):956-60. PubMed.
17Beta-estradiol enhances leptin expression in human placental cells through genomic and nongenomic actions.
Gambino YP, Maymó JL, Pérez-Pérez A, Dueñas JL, Sánchez-Margalet V, Calvo JC, Varone CL.
Biol Reprod. 2010 Jul;83(1):42-51. PubMed.
Leptin stimulates protein synthesis-activating translation machinery in human trophoblastic cells.
Pérez-Pérez A, Maymó J, Gambino Y, Dueñas JL, Goberna R, Varone C, Sánchez-Margalet V.
Biol Reprod. 2009 Nov;81(5):826-32. PubMed.
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